A 41-year-old woman was administrated to our hospital. The patient complained about a recent body weight loss, alopecia as well as diarrhea. She also experienced psychentonia, insomnia and distending pain in the eyes. The patient was health before with no disease history in other systems. Her sister had similar symptoms and was receiving drug therapy. Physical examination showed that the patient was bilateral proptosis and hyperreflexia. The thyroid gland was swelling with no haphalgesia. Her arms were shaking when straightened. Laboratory examination showed that the serum TSH level was declined and the serum T4 level was increased. She was diagnosed with hyperthyroidism.Please answer the following questions according to the woman’s medical history:1. How was the relative stable state of the serum thyroxine level maintained in normal persons?2. Why was the serum TSH level of the hyperthyroidism patients declined?
A 41-year-old woman was administrated to our hospital. The patient complained about a recent body weight loss, alopecia as well as diarrhea. She also experienced psychentonia, insomnia and distending pain in the eyes. The patient was health before with no disease history in other systems. Her sister had similar symptoms and was receiving drug therapy. Physical examination showed that the patient was bilateral proptosis and hyperreflexia. The thyroid gland was swelling with no haphalgesia. Her arms were shaking when straightened. Laboratory examination showed that the serum TSH level was declined and the serum T4 level was increased. She was diagnosed with hyperthyroidism.Please answer the following questions according to the woman’s medical history:1. How was the relative stable state of the serum thyroxine level maintained in normal persons?2. Why was the serum TSH level of the hyperthyroidism patients declined?
